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Dr. Danny, Hon Fai So, Head of Oncology Service at Pangenia Inc., shares his experience with Nonacus and explains why he chose Nonacus over competitors. From superior gene coverage to customization which allows flexibility, Nonacus offers a comprehensive solution tailored to the needs of cancer researchers and diagnostic laboratories.
In this developing research technology era, selecting the right tools for genetic analysis is pivotal
Researchers and clinicians need:
- Reliable
- High-performance sequencing solutions
that provide accurate, efficient, and cost-effective results
The table of contents
Superior Gene Coverage for Comprehensive Cancer Analysis
Dr. Danny, Hon Fai So, Head of Oncology Service at Pangenia Inc., explains why Nonacus product stands out in the competitive landscape of oncology solutions. One of the key reasons for his choice is:
Nonacus’ hybridization-based model for library preparation which ensures complete gene coverage
“We don’t just look at hotspots. Many mutations involved in cancer pathogenesis span entire regions, affecting different kinase domains and binding sites. Nonacus offers superior whole-gene probe coverage, which ensures accurate sequencing results,”
Dr. So explains
Reliable and Validation on Probes for Enhanced Efficiency
Among the various suppliers evaluated,
Nonacus emerged as the most reliable due to its pre-validation process
Unlike other companies that require customers to conduct their own probe efficiency evaluations, Nonacus pre-validates its in-house; saving time, money, and precious patient samples.
“Nonacus guarantees probe coverage efficiency before we even start using the,. This pre-validation is crucial, allowing us to focus on research and analysis without the additional burden of testing,”
Dr. So says
Customization Offers Flexibility for Tailored Region-Specific Oncology Research
Another major advantage of Nonacus products is that
Nonacus offers panel customization
Dr. So and his team require a genetic panel tailored to the specific cancer pathogenesis-related genes prevalent in their region. To achieve this, they designed a panel based on genetic databases from Mainland China, Hong Kong, Taiwan, Korea, and Japan.
“Nonacus allows us to integrate region-specific genetic markers that may not be as relevant in Europe but are crucial for cancer research in Asia. This flexibility ensures our panel aligns with local genetic variations, making it an ideal tool for both research and patient diagnostics,”
Dr. So notes
Targeted Panel Design for Optimal Cancer Research
Rather than performing whole-exome or whole-genome sequencing, which involves over 20,000 genes, Dr. So‘s team focuses on a carefully curated panel of approximately 400 genes. this targeted approach ensures efficient and insightful analysis.
“By concentrating on a relevant gene set, we maximize sequencing efficiency and ensure insightful data output for both research and patient applications,”
Dr. So highlights
Versatility Across Multiple Sample Types
Nonacus’ product adaptability to various sample types is a game-changer
Dr. So‘s team works with blood plasma, FFPE tissues, urine, cerebrospinal fluid (CSF), and more.
“We use Nonacus kits for both liquid biopsy and tissue samples. The availability of fragmentation and non-fragmentation kits allows us to work across diverse applications, including hereditary and germline mutation research,”
he explains
For Dr. So and his team, Nonacus’ combination of comprehensive gene coverage, validated probes, customization flexibility, multi-sample compatibility, and cost-effectiveness makes it the ultimate choice for oncology research and diagnostics.
“Nonacus provides the reliability, efficiency, and flexibility we need to push cancer research forward while delivering high-quality results,” he concludes.